Cosmetic grade
PDRN Solution
A ready-to-use aqueous grade prepared to your target concentration.
FormatAqueous
GradeCosmetic
MOQOn request
Cosmetic grade
Images are illustrative. Actual product appearance is confirmed in the batch COA.
PDRN Powder
Polydeoxyribonucleotide · Cosmetic raw material
A cosmetic-grade PDRN powder for formulators who need a precise, water-soluble active with batch-level documentation. Suitable for serums, essences, ampoules and hydrogel systems.
INCISodium DNA
CAS100403-24-5
Assay≥99.0% (dried basis)
AppearanceWhite / off-white powder or granules
Molecular weight60–100 kDa
Shelf life2 years, sealed
Batch-specific COA
Samples available
Global shipping
Response in 1 business day
For cosmetic formulation only. Not for injection, therapeutic use or direct consumer sale. Please review the MSDS before handling.
A cosmetic active with a clean paper trail.
PDRN Powder is produced from salmon-derived DNA through controlled fragmentation and purification, then processed into a stable powder. The result is a water-soluble raw material that is straightforward to weigh, dissolve and incorporate into water-based cosmetic systems.
Each batch is tested for identity, purity and microbiological quality. The batch-specific Certificate of Analysis travels with the material, so your formulation and regulatory teams can review the actual results — not just a marketing sheet.
Why formulators choose this grade
- Water-soluble and compatible with many common cosmetic bases.
- Powder format supports stable storage and transport.
- Controlled molecular weight range for batch-to-batch consistency.
- COA and MSDS available; TDS on request.
- Samples available on request for bench-scale evaluation.
How to incorporate
Disperse the powder in the water phase with gentle mixing. Add during the cool-down stage to limit heat exposure, and validate the final pH and stability in your own base. A typical starting point is 0.1–2.0% in the final formula.
Typical specification.
Values below are typical for cosmetic-grade PDRN Powder. The batch-specific COA is the controlling document for each shipment.
| Parameter | Specification |
|---|---|
| Product name | Polydeoxyribonucleotide (PDRN) |
| INCI name | Sodium DNA |
| CAS number | 100403-24-5 |
| Source | Salmon |
| Grade | Cosmetic grade |
| Appearance | White, off-white or slightly yellow powder or granules |
| UV identification | 260 nm / 280 nm absorbance ratio 1.8–2.0 |
| Assay | ≥99.0% (on dried basis) |
| Molecular weight | 60–100 kDa |
| Solubility | Soluble in water |
| pH | 6.0–8.0 |
| Loss on drying | ≤10.0% |
| Protein | ≤1.0% |
| Heavy metals | Pb ≤10 mg/kg · As ≤2 mg/kg · Hg ≤1 mg/kg · Cd ≤5 mg/kg |
| Microbial limits | Total plate count <1,000 CFU/g · yeast & mould <50 CFU/g · E. coli and Salmonella negative |
| Shelf life | 2 years, sealed |
| Storage | Store in a cool, dry place; protect from light and heat |
| Packaging | Plastic bag inside, aluminum foil bag outside |
| MOQ | On request |
Where PDRN fits.
Because PDRN is water-soluble, it is easiest to incorporate in aqueous systems. Typical starting points are shown below; confirm the final level in your formula.
01 / SERUMS & ESSENCES
Clear, lightweight systems
0.1–2.0% typical use level. Add to the water phase and check clarity and pH.
02 / AMPOULES
Concentrated formats
0.5–2.0% typical use level. Consider preservative strategy and single-dose packaging.
03 / GELS & MASKS
Hydrogel and gel-cream
0.1–1.0% typical use level. Test compatibility with your gelling system.
Compatibility notes
PDRN is generally compatible with common water-based cosmetic ingredients. As with any active, we recommend a compatibility and stability screen before scaling up.
- Works in water, water/glycol and hydrogel systems.
- Add during cool-down and avoid prolonged high heat.
- Check pH after addition; the target range is 6.0–8.0.
- Preservative selection should be validated for your final formula.
Documents that travel with the batch.
Download a representative document below, or request the current batch-specific COA for your shipment.
Certificate of Analysis
Batch ES-260825-01 · PDF
Download COA →
Technical Data Sheet
Issued against your specification
Request TDS →
Material Safety Data Sheet
Handling & safety · PDF
Download MSDS →
Need the current batch COA?
Send us your product and quantity, and we'll return the matching batch documentation.
Request COA
The COA shown is batch ES-260825-01. A signed, batch-specific COA is issued with each order. The MSDS supports safe handling and does not replace a site-specific risk assessment.
Questions formulators ask.
What is PDRN?
PDRN stands for polydeoxyribonucleotide: a family of low-molecular-weight DNA fragments derived from salmon. In cosmetics it is used as a skin-conditioning ingredient in water-based formulas such as serums, essences and gels.
Is this PDRN grade intended for injection?
No. This is a cosmetic-grade raw material intended for topical cosmetic formulations only. It is not supplied for injection, therapeutic use or direct consumer sale. If you are developing an injectable product, you need a pharmaceutical-grade material and the appropriate regulatory pathway.
What is the recommended use level?
A typical starting point is 0.1–2.0% in the final formula, depending on the format and your formulation goals. Confirm the final use level through your own stability, compatibility and safety testing.
How should PDRN Powder be stored?
Store sealed in a cool, dry place, protected from light and heat. Allow the container to reach room temperature before opening to reduce condensation. Once reconstituted, follow your own microbial and stability controls.
Can I request a sample?
Yes. Samples are available on request for the powder grade. Use the request form or email winnie@esurey.com with your application and shipping country.
Is PDRN compatible with hyaluronic acid and niacinamide?
PDRN is generally compatible with common water-based cosmetic ingredients, including hyaluronic acid and niacinamide. However, every formula is different. We recommend a small compatibility and stability trial before scaling up.
Related formats
More ways to work with PDRN.
Prefer a liquid system or a related nucleotide grade? Explore the rest of the range.
View all products
Cosmetic grade
Nucleotide grade
PN (Polynucleotide)
A related nucleotide ingredient for formulators exploring the PDRN family.
GradeCosmetic
SpecOn request
MOQOn request
Plant-derived
Plant PDRN
A plant-derived nucleotide alternative for non-animal positioning.
SourceBotanical
GradeCosmetic
MOQOn request
Sample request
Put PDRN Powder through your own process.
Tell us your application and shipping country. We'll confirm availability, share the current batch documents and arrange a sample.